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CO 2 is a potent regulator of CBF, as elevated CO 2 and the accompanying pH change causes healthy cerebral arterioles to dilate, subsequently increasing conductance and CBF (Hoiland et al., 2019)

Whilst increased heart rate was documented as a common finding, the pattern and magnitude did not meet criteria for POTS diagnosis

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In addition, alcohol can cause inflammation throughout the body, which can further weaken immunity