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doi: 10.1159/000485132

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One mechanism that contributes to cytochrome c detachment from IMM involves cardiolipin oxidation because oxidized cardiolipin has a much lower affinity for cytochrome c than the reduced form

Semaglutide targets the GLP-1 pathway exclusively, while tirzepatide stimulates both GLP-1 and GIP receptors, a combination that clinical evidence suggests may produce stronger appetite suppression and metabolic effects