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6.2.2 Therapeutic strategies targeting astrocytic ferroptosis Astrocytes, the most abundant glial cells in the central nervous system, play essential roles in supporting neuronal function, regulating antioxidant defense, and maintaining metabolic homeostasis

For people with high cardiovascular risk, the NSAID naproxen is typically recommended because it has been associated with fewer cardiovascular events compared with other NSAIDs in several studies (Conaghan 2012)

used Cre-lox technology to delete the gene encoding the GLP-1R specifically in the CNS to reveal that GLP-1R agonist-induced weight loss requires GLP-1Rs in the CNS [13]

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