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For tirzepatide, maintenance doses typically fall between 2.5 mg and 7.5 mg, down from the therapeutic 10 to 15 mg

Because tirzepatide targets both GLP-1 and GIP receptors, researchers are evaluating whether dual agonist therapies may produce even greater functional improvement in obesity-related osteoarthritis

After consulting with his endocrinologist and reducing his dose to 5 mg, plus increasing his protein intake, Holcombe said he has been able to maintain glycemic control without losing muscle mass

Symptoms often ease within weeks as your body adapts and intake stabilises again