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e-g , Muscle bulk RNA-Seq data presented as a heatmap focusing on: upregulated genes involved in oxidative stress, cellular metabolic process, branched chain amino acid metabolism, NAD, and pantetheinase (e), downregulated genes in extracellular organization and animal organ development (f), and genes in the ISR that appear minimally affected (g) in KO compared to Het mice at Day 2 on No Cys diet (See also Supplementary Table 3)

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Expert Rev Gastroenterol Hepatol