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Many Michigan employer-sponsored plans exclude AOMs entirely, which is legal under the Employee Retirement Income Security Act (ERISA) as written in 2026

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Medication adjustments may be considered in consultation with prescribing clinicians: Dose reduction : Lowering the Ozempic dose may reduce symptom severity whilst maintaining some glycaemic benefit Slower titration : Increasing the dose more gradually than standard protocols may improve tolerability Prokinetic agents : In the UK, medications such as metoclopramide are generally restricted to short-term use (maximum 5 days) due to neurological side effect risks

Shimu has been focused on research and development for many years and the investment in R&D increase with years

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