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Clinical trials for this age group are ongoing, but there is currently no established safety or efficacy data for children or adolescents
They are currently recommended for: Individuals with a BMI over 30 (classified as obese), or Individuals with a BMI over 27 who also have weight-related health issues (such as hypertension, type 2 diabetes, or high cholesterol)
It stimulates insulin secretion from pancreatic beta cells in a glucose-dependent manner, meaning insulin is only released when blood glucose levels are elevated
[RELATED: Semaglutide Reduces Risk of Worsening Heart Failure in HFpEF] Many studies point to obesity as a major contributor to the development and severity of heart failure with a preserved ejection fraction through its effects to promote systemic and myocardial inflammation, says Milton Packer, MD, distinguished scholar in cardiovascular science at Baylor University Medical Center at Dallas and visiting professor at Imperial College, London (steering committee chair), in a release
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