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Both drugs are administered via subcutaneous injection, but they differ in their duration of action
Similarly, GLP-1R activation on the axons from dispersed SPNs in the ICN, and possibly CAA, may account for other, rarer side effects of GLP-1R agonists
This high receptor affinity allows for effective receptor activation even at lower drug concentrations, potentially reducing the risk of side effects associated with higher doses
When the iron load increases (such as high iron reserve level, high serum iron) 25 or in cases of infection and chronic inflammation, 26 elevated hepcidin directly binds to membrane FPN, promoting its internalization as well as degradation in epithelial cells of intestinal, thereby inhibiting iron absorption into the blood
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