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Autophagy 16 , 317 (2020)

found that dietary Gln supplementation can elevate Gln levels in the TME, decrease the expression of immunosuppressive genes such as Ctla4 and Nrp1 in Tregs, inhibit Treg differentiation, and consequently enhance the tumor immune response (52)

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(PubMed) Zimmermann MB, Galetti V

Even more, ellagic acid has additionally been shown to increase monoamine oxidase B (MAO-B), nuclear factor (erythrocyte derivation 2), Nrf2, and heme oxygenase 1 (HO-1) and reduce the loss of tyrosine hydroxylase (TH)-positive neurons in the substantia nigra pars compacta (SNC) (Sarkaki et al., 2016)