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The ERs then recruit transcriptional complexes and other co-regulatory factors to specific DNA sequences known as estrogen responsive elements, thereby modulating target gene transcription (30)

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Therefore, tPA reduced mortality and respiratory distress as well as normalized hypoxemia and hypercarbia induced by lethal SM inhalation which suggest the therapeutic effect of tPA on SM-induced lung disorders

Mingorance, C., Duluc, L., Chalopin, M., & Andriantsitohaina, R

RNA nanotechnology has emerged as a promising modality for targeted delivery of chemotherapeutics