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According to the FDA's press release it agreed to approve the drug for obesity based on three randomised, double-blind, placebo-controlled trials during which more than 2,600 patients received Wegovy for up to 68 weeks and more than 1,500 patients received placebo (US FDA 2021)

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Mechanisms and Differences of CJC-1295 and Ipamorelin CJC-1295 acts via the GHRH receptor on the anterior pituitary to stimulate GH release and sustain its secretion, maintaining the natural pulsatile rhythm rather than causing a flat, constant output

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