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The exposure of PC cells to physiological concentrations of zinc (0.010.5 mM) can lead to cytotoxic cell death, which is characterized by up-regulation of the zinc transporter ZnT1 gene expression

We find that ferroptosis suppressor protein 1 (FSP1), a ubiquinone oxidoreductase, is the enzyme responsible for vitamin K reduction in a warfarin-resistant manner, consistent with a recent discovery by Mishima et al

have type 1 diabetes or have had diabetic ketoacidosis

This suggests that GHK-Cu, a copper complex recognized for its healing capacities, might have a role in reducing inflammation and preventing tissue breakdown in models of ischemic wounds, where blood flow restriction potentially causes tissue damage