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While C/EBP and C/EBP primarily regulate differentiation, growth, and apoptosis in myeloid cells, C/EBP is essential in Ly6C + monocyte vitality and the broader regulation of MDSCs survival [81]

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Ethics declarations Institutional review board The study was conducted using 8-week-old ICR mice of the Specific Pathogen Free (SPF) category, provided by the Experimental Animal Center of Xuzhou Medical University, with ethical approval granted by the Xuzhou Medical University Ethics Committee (Ethical Approval Number: 202312T043, Approval Date: 29/12/2023)