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Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosis

Primary antibodies against SLC7A11 (Cell Signaling Technology, 12691, 1:500 dilution), iNOS (BD Biosciences, 610329, 1:500 dilution), 15LO1 (Abnova, H00000246-D01P, 1:1000 dilution), GPX4 (Abcam, 125066, 1:1000 dilution), POSTN (Santa Cruz Biotechnology, 67233, 1:500), and CCL26 (R&D Systems, AF653, 1:500 dilution) were used

Glutathione injections are one way to supplement this naturally occurring antioxidant under the guidance of a healthcare professional

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5a), suggesting that Pelo and Hbs1 may undergo the ubiquitinated degradation in the male reproductive organ