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The first-line nod was backed by interim data from the Phase III COMMANDS trial, which pitted Reblozyl against the ESA standard of care treatment, Amgen and Johnson & Johnsons Epogen/Procrit

Lilly supported its application for Ebglyss with data from the Phase III ADvocate 1 and ADvocate 2 studies, in which 38% of patients on the treatment saw clear or almost-clear skin after 16 weeks

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Few studies exist evaluating GHK-Cu for alopecia and so specific studies on effective concentration for this indication are unavailable, anecdotally some compounders use 0.2-3%