When administered as a once-weekly subcutaneous injection, Ozempic helps to: Stimulate insulin secretion from the pancreas in response to elevated blood glucose levels Suppress glucagon release , reducing the liver's production of glucose Slow gastric emptying , which helps control post-meal blood sugar spikes Reduce appetite , often leading to weight loss as a secondary benefit The mechanism of action centres on the GLP-1 receptor, which is found in various tissues including the pancreas, brain, and gastrointestinal tract
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The studys limitations include residual confounding, unexplored dose-response relationships, lack of age stratification, and limited adjustment for multiple testing
they should not be taken as evidence of equivalent efficacy
Less Common but Serious Concerns Gallbladder disease Pancreatitis (rare) Dehydration from persistent nausea At Florida Endocrinology and Diabetes Center, careful titration and monitoring minimize these risks
