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Drug Target 17 (7), 543552

Studies have reported OCTN2 expression in respiratory epithelial cells and alveolar macrophages, which is especially high in the upper lung region [301], and OCTN2-mediated carnitine uptake plays an important role in maintaining respiratory cilia beating and airway mucociliary clearance function, helping to remove excess mucus and potentially harmful substances from the airway [302]

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Depending on the type of interaction, various cellular effects might be observed, from the activation of the antioxidant system to the initiation of the biosynthesis of pro-inflammatory proteins 161