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The SURMOUNT trials tested specific titration speeds and found that slower escalation significantly reduced gastrointestinal side effects

The therapeutic window appears quite wide, with most users experiencing benefits without significant side effects across a range of doses

They founcd that OMT induced cell death and inhibited proliferation in HCC cells, while simultaneously downregulating the expression of YY1 and GPX4 and upregulating SIRT1 expression

In addition, loss of lean muscle mass is a serious concern, as some users end up with poorer body composition following treatment

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