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NAFLDsym simulations combined the predicted exposure of 24 g BID dosing with various combinations and strengths of candidate MoAs

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The reduction or absence of -globin within the erythroblasts of those with -thal causes a discrepancy in the proportion of -globin and -globin over the development of erythroid cells

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Briefly, cells were stained with C11-Bodipy (2 M) for 30 min at 37 C