After the initial reduction in appetite, the food intake of the experimental groups increased to the same amount as the rats in the control group, however, both the high dose and low dose groups were seen to have maintained a lower level of body weight despite the increase in calories
Cecchelli R, Aday S, Sevin E, Almeida C, Culot M, Dehouck L, et al
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Speculation regarding cause has invoked developmental factors or hormonal changes such as occur in adolescence and pregnancy
Treatment with the glucagon receptor antagonist LY2409021 increases ambulatory blood pressure in patients with type 2 diabetes