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Melanotan-2 binds to melanocortin-1 receptors (MC1R) on melanocytes in the basal epidermis, triggering a cAMP-mediated signaling cascade that activates microphthalmia-associated transcription factor (MITF)

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CJC-1295 is a long-acting analog of growth hormone-releasing hormone (GHRH) that activates GHRH receptors in the pituitary, triggering robust and sustained GH secretion via the cAMP/PKA pathway