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Previous animal studies have also detected reduced Hcy concentrations after creatine supplementation ( Reference Taes, Delanghe and De Vriese 6 , Reference Stead, Au and Jacobs 20 )

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Modest Weight-Neutral or Loss Effect: While not a primary weight loss drug, metformin is generally considered weight-neutral and in some cases, can lead to a modest amount of weight loss, which can be an added benefit for many individuals