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434 Patients with PDPN have increased epineurial blood flow and intravascular oxygen saturation, perhaps secondary to arteriovenous shunting due to sympathetic denervation

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This innovative strategy of integrating the complementary actions of multiple endogenous metabolically related hormones into a single molecule is considered one of the most promising approaches for the treatment of obesity and its comorbidities

doi:10.1016/j.tics.2010.11.001 7

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