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Triglyceride-lowering effects appear particularly robust in patients with elevated baseline levels

Tissue remodeling mechanisms

Additionally, GIP receptor expression in hypothalamic regions and oligodendrocytes suggests central nervous system actions that may synergize with GLP-1 to reduce appetite and food intake while potentially mitigating GLP-1-associated nausea, thereby improving treatment tolerability [36,41,42]

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Aitken, Murray, Nass, Deanna, Digital Health Trends 2024: Implications for Research and Patient Care, IQVIA Institute for Human Data Science, Dec, 2024, 9