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[16] [18] Current clinical guidelines recommend caution and individualized decision-making, given the lack of robust safety data for high-dose injectable vitamin C in pregnancy and lactation

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After 1 year, 55.4% of the patients (4494493 out of 1595) who received lorcaserin and 45.1% of the patients (716 out of 154497) who received the placebo remained in the trial, and 1553 patients continued into the second year

Eight weeks of supplementation (2 g/day) combined with aerobic training (3 sessions a week) had no significant effects on body weight, BMI and daily dietary intake in obese women [42]