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New England Journal of Medicine (2025) 2
The publication of high-quality mechanistic studies, coupled with small human trials showing functional endocrine and immune effects , has elevated the peptide from fringe curiosity to a serious candidate in the longevity toolkit
As both play very important roles in the immune response, and the status or availability of one has been shown to directly affect the other, it is likely that deficiency of either can have a direct effect on the severity of COVID-19 as well as many other diseases therefore, taking steps to ensure adequate levels of both is essential to better health
Start slowly with shorter fasting windows (12 hours fasting, 12 hours eating) and gradually build up
Fredborg, M., Theil, P
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