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United States list prices are set with the expectation of confidential rebates negotiated between manufacturers and pharmacy benefit managers, and cash payers transact outside that structure

In the UK, several classes of laxatives are available over the counter or on prescription, each with distinct mechanisms of action and safety profiles

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doi: 10.3390/toxins12120741 16 BartochowskiP.GayrardN.BornesS.DruartC.ArgilsA.Cordaillat-SimmonsM.et al