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Diseases with an autoimmune component damage particular cells mitochondrion

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In parallel with these changes, a decrease in the activity of antioxidant enzymes (GPx, CAT, GR, SOD) and GSH was noted ( 4.1 Oxidative stress in HT There are a growing number of reports showing that increased oxidative stress pathways lead to increased synthesis and release of a wide variety of immune and inflammatory molecules

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doi:10.1096/fba.2021-00022 13