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Furthermore, the 5xFAD mouse, which overexpresses human APP with three mutations along with human presenilin 1 (PS1) harboring two mutations, begins to show significant apathy-like behaviors from six months of age, as measured by nest-building, burrowing, and marble burying (Keszycki et al., 2021

Haigis MC, Mostoslavsky R, Haigis KM, Fahie K, Christodoulou DC, Murphy AJJ, et al

Look for electrolyte drinks or supplements that provide sodium, potassium, and magnesium without excessive sugar

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