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However, many of these technologies remain preclinical or are early in development, and larger-scale, longer-term studies are required to more conclusively assess their long-term effectiveness, safety, and cost-efficiency before routine clinical use

Thats a big deal because it suggests semaglutide may be boosting heart health directly, perhaps in addition to the typical benefits that accompany weight loss, says Caroline Apovian, an obesity medicine specialist at Harvard Medical School and Brigham and Womens Hospital in Boston

Establish your baseline before starting the combination, and set clear thresholds with your provider for when to contact them

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