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It works by blocking tyrosinase, the enzyme that produces melanin, helping to fade dark spots, melasma, sun damage, and uneven skin tone over time

We also sought comments on not producing a preliminary list of ASM participants using 2024 data for the 2027 ASM performance year/2029 ASM payment year and only identifying the final ASM participants using applicable data from the 2025 calendar year

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Uncropped scan images were provided in the Source Data file