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This cascade induces endoplasmic reticulum stress and mitochondrial damage in ECs, leading to apoptosis [111, 112]

Peptides + Hormonal Therapies (e.g., Growth Hormone or IGF-1) Evidence: PDA and similar peptides work well with growth hormone-releasing peptides (GHRPs) or IGF-1, optimizing the anabolic environment for tissue repair

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It's worth noting that recovery follows a predictable pattern: blood cell production typically begins improving within 3-5 days, haemoglobin rises over 1-2 months, while neurological recovery may take several months

The decision depends on function and quality of life, not imaging alone