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A 24-hour urine profile is a useful tool in determining the type of stone(s) a patient has or is prone to developing (LabCorp 2015)

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5.2 Hypopituitarism In the Iglesias study, hypopituitarism at the time of PRLoma diagnosis was found in about 75% of patients and was more frequently diagnosed in patients with macro- than microPRLomas (111, 130133), which most likely should be related to tumor diameter (134)

41589_2021_915_MOESM11_ESM.mpeg Supplementary Video 9 Representative movie for 100 ns MD simulation of GPX4 U46C-K48L with the camera zoomed in for a close-up of the active site