PlexusDx offers alternatives including the microdose GLP-1 protocol ($129/month), oral formulations, or the Precision Peptide Genetic Test to identify which peptide pathways may carry lower gastrointestinal burden for your genetics
The second generation somatostatin analog pasireotide has been shown to induce impaired glucose tolerance, overt diabetes or worsen glycemic control especially in patients with pre-existing disturbed glucose metabolism (52)
These data points are compatible with the notion that dual-pathway stimulation of pituitary somatotrophs may produce a markedly greater IGF-1 increase than either peptide alone
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Daniele C, Thompson Coon J, Pittler MH, Ernst E