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While the biochemical mechanisms underlying the neurological effects of vitamin B 12 deficiency are not understood, the vitamin deficiency is known to damage the myelin sheath covering cranial, spinal, and peripheral nerves (42, 43)
10 Many efforts have been made in response to each process of the drug transportation, which have also been accompanied by reviews of latest progress in this field, but most of literature emphasize the BBB breakdown in specific brain disorders, 11,12,13,14 or give a general review of delivery strategies concentrating on the barrier physiology
After reconstitution, keep refrigerated (28C) and use within the timeframes specified by research protocols
Large intestinal blockages: Severe constipation can harden into stool that blocks the colon Fecal impaction: Intestinal obstruction caused by hardened stools
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