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It is not used for treating type 1 diabetes or for people with diabetic ketoacidosis

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The histone deacetylase inhibitor trichostatin A induces GADD45 gamma expression via Oct and NF-Y binding sites

Subsequent hits include imbalances in adipokines and cytokines, exposure to intestinal bacterial toxins, and increased oxidative stress

Sturgeon C, Lan J, Fasano A