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Considering that some of the GLP-1R agonists also decrease body weight, these have received approval for the treatment of obesity in humans [for a review, see Following ingestion of a meal, the GLP-1 levels rapidly increase

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10.1534/genetics.119.302939 [DOI] [PMC free article] [PubMed] [Google Scholar] Izadi A., Ebrahimi S., Shirazi S., Taghizadeh S., Parizad M., Farzadi L., et al

Excess weight increases the risk of type 2 diabetes, high blood pressure, heart disease, fatty liver disease, sleep apnea, joint pain, stroke, and some cancers