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Animal studies have emphasized the efficiency of the glymphatic system in purging waste from the brain, with peak effectiveness during sleep [14], particularly at night [204], and reduced efficacy observed in animal models of hypertension [205]
One of the known AdSS inhibitors is hadacidin, which are a natural antibiotic (the fermentation product of Penicillium frequentans ) and an analogue of L-aspartate (Tibrewal and Elliott 2011)
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3 Nutrient-related complications and their impact on rehabilitation 3.1 Diabetic peripheral neuropathy (DPN) A common and crippling side effect of T2DM, DPN affects roughly 50% of people with the disease and severely lowers quality of life (87, 88)
