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Individual variability in response to tirzepatide is common and may be influenced by multiple factors including genetics, though these relationships are not fully characterized in current research

Altered Food Preferences: Some individuals report changes in taste perception, particularly a reduced preference for fatty and highly processed foods, suggesting GLP-1 medications reshape dietary behavior beyond just appetite suppression

Use a food and symptom journal to identify patterns

For patients who cannot tolerate higher-potency GLP-1 therapies or who prefer a longer-established safety profile, Saxenda may be a reasonable option

Shimamoto, G., Gegg, C., Boone, T