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They draw water into the intestines, which softens the stool and stimulates a bowel movement

Hydrate between meals, not during

The Maintenance Phase (Week 17 and Onward) Ultimately, the goal of titration is to reach a maintenance dose that effectively supports your weight loss goals with tolerable side effects

You can hold the pen or vial in your hands for a few minutes to speed the process

Comparing the medications side by side for alternating decisions This comparison table helps visualize the key differences that affect alternating protocols: For a detailed comparison of how these medications stack up across additional factors, the semaglutide versus tirzepatide comparison page provides comprehensive analysis