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There was no difference in SDMA blood levels in O- and L-ZSF1 (0.301 0.028 M and 0.308 0.047 M, p = 1.00) (Fig

We therefore hypothesize that following entry into the bloodstream, UA is converted into less biologically active phase II metabolites, which subsequently dissociate into more active UA monomers within tissues and inflammatory microenvironment (Figure 1)