It inhibits GPX4, leading to tumor-specific ferroptosis, and TA is used to chemically reduce Fe 3+ to Fe 2+ and continuously supply Fe 2+ to maintain the iron redox cycle and maintain the Fenton reaction [201]
For example, you may experience nausea, cold symptoms, and diarrhea
Moreover, within the biological process category, cellular process, regulation of biological process, and biological regulation were identified as key processes
FIGURE 5 Discussion It is well known that BHBA has a neuroprotective effect in the central nervous system, but the underlying mechanisms are the subject of ongoing research
Some cytosolic GSH is transported, thanks to a specific transporter, the multidrug resistance protein 1 (MRP1), out of the cell to maintain a balance in the redox level [22], or can be conjugated by GSH transferases (GST) with endogenous metabolites, such as cysteinyl leukotriene or xenobiotics (therapeutics, anticancer drugs, carcinogens, pesticides, herbicides), forming a complex GSH-Xen, which is transported outside the cell by MRP1 [19]
