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142,222,225,385,386,387 It has also been demonstrated that the enzymes in glycolysis (e.g., GLUT4, HK1, GSK3B, and GAPDH), the enzymes (e.g., PDPR PDHA1, and PDHX) in carbohydrate metabolism, and most enzymes in ETC and ATP synthesis are assigned as ADP-ribose amino acid acceptor