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For instance, given the potent anti-inflammatory properties of GLP-1 agonists, which can reduce hs-CRP levels by 2030% [28], future trials could explore whether patients with a high baseline inflammatory burden (elevated hs-CRP) derive a disproportionately larger cardiovascular benefit [95]

Shi, Z., & Puyo, C

Extrapolating (modeled estimate), this suggests nearly 29M Americans and 2M Canadians are currently interested in GLP-1 mediations but havent asked their doctor yet

Three main paths exist: Weeks 37-48 Summary: Completion and Planning Weight loss: 3-7 pounds this period (49-53 pounds total, ~24% of starting weight average) Weekly loss rate: 0.25-0.6 pounds weekly (minimal but still progressing) Final results: 24.2% average total body weight loss by week 48 Discontinuation rate: 1-2% during this period Overall completion rate: 74% of people who started week 1 completed week 48 Psychological state: Proud of achievement, planning next steps What Actually Determines Your Timeline Results Individual timelines vary from the averages presented

Other weeks, particularly after dose increases , you might experience loose stools