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Sensitivity analyses Using other non-insulin glucose-lowering agents (excluding SGLT2i) as treatment comparator (60.8%, sulfonylureas

[4] Mozaffarian, D., Agarwal, M., Aggarwal, M., Alexander, L., Apovian, C

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In the last few years, various GSH modulation-enhanced combinational therapy strategies have been extensively exploited, accompanied by the development of versatile metal-based nanosystems with different structures, functionalities, and treatment performances ( In view of the rapid development of GSH-responsive and -exhausting metal nanomedicines in potentiating cancer therapy, we summarize and outline the recent advancements, mechanisms, prospects, and challenges in this field from different strategies (Scheme 1)