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Wright DJ, Gray LJ, Finkelstein DI, Crouch PJ, Pow D, Pang TY, et al

Forty-two four-week-old male Sprague-Dawley (SD) rats were divided into seven groups: anti-LOX, control, VED, HCG, anti-LOX and VED, VED and HCG, and VED+HCG+anti-LOX

There was no significant advantage for conception with the addition of metformin compared to myo-inositol alone

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Pregnancy/lactation insufficient safety data for supplemental use