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The FDA warned against the use of compounded semaglutide more broadly, noting that these reformulated therapies pose a higher risk to patients than approved medicines because they do not undergo FDA premarket review for safety, effectiveness or quality. Patients should only be on compounded medication if their medical needs cannot be met by an available FDA-approved drug. Weight-loss therapies have been growing rapidly in recent months, with Novo Nordisks Wegovy (semaglutide) and Eli Lillys Zepbound (tirzepatide) currently dominating the space and other competitors looking target the lucrative market

Bottom line: We dont know yet how, or if, GLP-1 drugs cause NAION or other eye problems

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This gradual approach allows the gastrointestinal system to readjust while improving long-term adherence