Tretinoin, a prescription vitamin A derivative, has been called the most potent and certainly the most widely investigated retinoid for photoaging therapy by researchers in a 2006 review.49 And a more recent 2022 review notes that studies on tretinoin consistently find it to be efficacious in improving [the] clinical appearance of photoaging.50 And many nonprescription ingredients, like niacinamide (for melasma),51 vitamin C (for wrinkles),52 and hyaluronic acid (for dry skin), have demonstrated positive outcomes in studies.53 Some of our favorite online dermatology options that weve reviewed are Curology, Agency, Prose, and Musely
P., Reid, M., Balasubramanyam, A., Taffet, G
Research shows: A 1998 study did find that applying oleic acid at higher concentrations may cause irritation and disrupt the skin barrier
10.1039/d0np00057d Nat Prod Rep
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