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For the creation of neurotransmitters and the upkeep of neurons, copper is a crucial component of brain chemistry

Figure 1 Regulatory mechanism (Figure 1): The essence of ferroptosis lies in the depletion of glutathione (GSH) and the decline in the activity of glutathione peroxidase (GPX4), which leads to a reduction in the amount of glutathione reductase catalyzed by GPX4 and excessive accumulation of lipid peroxides (10)

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Gut microbiota-derived butyrate induces epigenetic and metabolic reprogramming in myeloid-derived suppressor cells to alleviate primary biliary cholangitis