In the future, we will continue to study the pharmacology, pharmacokinetics and toxicology of these drugs, as well as evaluating their efficacy and safety in clinical trials, with the aim of providing new approaches to the development of new agents for the treatment of lung cancer
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Although age and sex were not included as covariates in the PERMANOVA models, participants were age- and sex-matched at recruitment
JNK1/2 (c-Jun N-terminal kinases) show slight inhibition with reduced phosphorylation, though effects are less pronounced than p38 MAPK pathway changes
These results suggest that NAC can alleviate genotoxic stress and apoptosis triggered by environmental toxins, thereby underscoring its therapeutic potential in maintaining genomic integrity and neuronal function in oxidative environments [10]